PKC eta anticorps (AA 30-389)

N° du produit ABIN4952175

Cet anticorps Lapin Polyclonal détecte spécifiquement PKC eta dans WB et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour PKC eta anticorps (AA 30-389) (ABIN4952175)

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC eta est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-PKC eta anticorps

Épitope: AA 30-389

Purification: Antigen affinity

Immunogène: Amino acids 30-389 of human PKC eta were used as the immunogen for the PKC eta antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PKC eta antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,FACS: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the PKC eta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur PKC eta

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Autre désignation: PKC eta

Sujet: PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

UniProt: P24723

Pathways: Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling